Optimization of the clinical diagnostic examination algorithm of patients with a cross bite complicated by cranio-mandibular dysfunction and postural disorder.

OBJECTIVE: Aim: Optimization of the clinical and diagnostic examination algorithm of patients with cross bite, aggravated by cranio-mandibular dysfunction and postural disorders. PATIENTS AND METHODS: Materials and Methods: 22 patients aged 13-16 years with cross bite with displacement of the lower jaw were examined. The first group consisted of 15 people with a right-sided displacement of the lower jaw, the second - 7 patients with a left-sided one. The condition of the musculoskeletal system was assessed by the position of the head, shoulders, shoulder blades, back (curvature of the spine), legs, chest shape, and abdomen. To determine the state of stability of the body in space, posturological and kinesiological tests were performed. The location of TMJ elements was evaluated on orthopantomograms. Statistical processing of the material was carried out with the help of the "Excel" license package. RESULTS: Results: 63.64% of patients with a cross bite have disorders of the musculoskeletal system: scoliotic posture - 40.91% and scoliosis - 22.73%. TMJ dysfunction was detected in all examined patients. It was established that the anatomical and topographic features of the joint elements depend on the side of the lower jaw displacement. CONCLUSION: Conclusions: The functional imbalance of all structural elements of the musculoskeletal system and the cranio-mandibular complex determined during the research proved the need to optimize the clinical-diagnostic algorithm: consultation of a traumatologist-orthopedic doctor, X-ray examination of TMJ, conducting posturological tests.

Influence of pallet rich plasma, quercetin and their combination on activity of nitric oxide cycle enzymes in nasal mucosa of patients with atrophic rhinitis.

OBJECTIVE: Aim: To study the general activity of NO synthases (gNOS), the activity of inducible and constitutive isoforms of NO synthase, the activity of arginases, and the concentration of nitrites in the nasal mucosa under the conditions of local treatment of chronic atrophic rhinitis (AR) with quercetin and platelet-rich plasma (PRP therapy).. PATIENTS AND METHODS: Materials and Methods: The study was conducted on 118 patients divided into two groups: control (n=20) and experimental (patients with AR, n=98). Experimental group was divided into 4 subgroups: standard treatment (n=29), PRP therapy (6 injections for 28 day course, n=19), Quercetin (40 mg 3 times a day for 28 days, n=26) and PRP+Quercetin (n=24) groups. RESULTS: Results: Standard therapy of SaR increases gNOS by 278.38% and arginase activity increases by 222.73%. PRP therapy increases gNOS by 211.43% and arginase by 540.91%. Quercetin elevates gNOS by 108.33% and arginase by 250%. PRP therapy and quercetin increases gNOS by 146.15% and arginase by 536.36%. CONCLUSION: Conclusions: The use of standard therapy of SaR and addition of PRP therapy, quercetin and their combination effectively restores the production of nitric oxide and the arginase activity in the nasal mucosa.

MINERALIZATION OF TEETH ENAMEL AFTER ERUPTION.

OBJECTIVE: The aim: The paper was aimed at the study of the processes of mineralization of the enamel of the permanent tooth after its eruption. PATIENTS AND METHODS: Materials and methods: To study the structure of the enamel of permanent teeth has been carried out using light and electron microscopy. The study of the process of the development of the primordia of the permanent teeth involved 10 culled puppies of 30-40 days of age. Microscopic, electron microscopic, immunohistochemical methods of research have been used to study the processes of histogenesis. RESULTS: Results: The studies show that in the postnatal period, the formation of the crown, externally covered with cuticular epithelium, marks the formation of the primordium of the permanent tooth at the follicle stage. After eruption of a tooth, different parts of its crown have three individual structural and functional barriers to enamel biomineralization. The first one is provided by the cuticular epithelium of the pitted areas of the crown, which ensures filtering of the salivary fluid from the protein deposit in the form of a pellicle. The second barrier is defined on the lateral and cuspidate surfaces of the enamel, where the cuticle is erased or poorly expressed. The third structural and functional barrier of enamel biomineralization is located in the cervical portion of teeth of different classes. CONCLUSION: Conclusions: Different areas of the enamel in the tooth crown have specific filtration barriers, which can be distinguished as follows: pit-and-fissure-and-groove, cuspidateand-approximal, and cervical barriers. The cuticle is poorly expressed or totally absent on the cusps of the tooth crowns in contrast to pitted areas.

STUDYING AND ANALYZE THE FACTORS THAT AFFECT COMPLIANCE DENTIST RECOMMENDATIONS FROM PARENTS OF CHILD PATIENTS.

OBJECTIVE: The aim: Investigate the factors that influence the tendency of parents to follow the advice of a dentist on the way to improving the dental health of their children and build a prognostic model. PATIENTS AND METHODS: Materials and methods: Materials: we analyzed 406 questionnaires (specially created by the author), which contain the answers of parents of schoolchildren of Poltava. Methods: questionnaires, medical and statistical, modeling. RESULTS: Results: The statistical processing of the questionnaires revealed a number of factors those that affect parents' compliance with the advice of a dentist, increasing or decreasing the chances of it: low sanitary and hygienic awareness of parents; non-observance of hygiene rules by parents; parents do not teach the child to care for the oral cavity;opinion of the parents that only state must take care of children's health; the recommendations of the dentist wasn`t received; child had never visited a dentist for prevention. The operational characteristics of the obtained prognostic model: the area under the curve is 0,762, which indicates a good predictability of the model. Sensitivity is 82,2%, specificity - 79,8%. CONCLUSION: Conclusions: The data obtained as a result of our study and the constructed prognostic model: they indicate low sanitary and hygienic awareness of parents, paternalism of their thinking (shifting responsibility to someone, unwillingness to take responsibility), lack of medical and hygienic knowledge, as a result of which they do not apply them to themselves and, of course, to their children. The solution to this problem is possible only through informational and explanatory activities with the involvement of modern methods of communication and people who have passed appropriate training.

DENTAL CROWN BIOMINERALIZATION DURING ITS HISTOGENESIS.

OBJECTIVE: The aim: Thepaper wasaimedat thestudyof thebiomineralization processesofa permanentdental crown in thepostnatal period of histogenesis. PATIENTS AND METHODS: Materials and methods: The study involved 30 culled puppies aged 30-40 days. To study the histogenesis of the germs of the permanent tooth from the cuticular epithelium in the postnatal period microscopic, electron microscopic, immunohistochemical methods of study have been used. RESULTS: Results: The studies show that in the postnatal period, the maturation of the germ of a permanent tooth starts with the synthesis of cells of the cuticular epithelium of the organic stroma, capable of subsequent mineralization. Differentiation of the proameloblasts, located on the surface of the dental papillary mesenchyma, at the early stages of histogenesis, is strongly associated with the appearance of a specific protein taftelin. Origination of secretory ameloblasts, which produce the protein enamelin, triggers the process of secondary biomineralization of the enamel. The terminal processes of the secretory ameloblasts produce the protein in the form of layers that overlap each other at a certain angle. Such layering of the structures of enamel and dentin contributes to the S-shaped maturation of the hard tooth tissues, strengthening them considerably. At the follicle stage, maturation of the dental crown, coated with cuticular epithelium, occurs. Invaginations of the cuticular epithelium form a characteristic topography of the dental crown, and enamel projections are further formed by the ameloblasts. Epitheliocytes of the inner layer of the enamel organ have desmosomal connections that allow the filtration of the salivary fluid at the stage of the enamel trophism. CONCLUSION: Conclusions: The findings of the study suggest that, normally, due to the cuticular epithelium, filtration of the salivary fluid occurs with protein deposition on it and subsequent infiltration of the calcium salts into the subjacent enamel.

X-ray analysis of the mandible in patients with crossbite and mandibular displacement.

OBJECTIVE: Introduction: Significant morphological and aesthetic disabilities of the face, observed during the formation of a cross bite in combination with the displacement of the mandible, prompt the doctors - orthodontists to study carefully the morphogenesis of this anomaly. The aim: Analysis of the mandible structure in patients with a cross bite and lower jaw displac ement based on the analysis of orthopantomograms. PATIENTS AND METHODS: Materials and methods: For this study, the orthodontic examination of 20 patients, 18-22 years old, was made they complained about facial asymmetry, displacement of the lower jaw and a violation of the cosmetic centers. A diagnosis of the buccal cross bite form in combination with the displacement of the lower jaw was put according to the Uzhumeckiene classification. The methods used do not contradict the conclusions of the ethics commission. RESULTS: Results: The analysis of the obtained data indicates that the angle of the mandible has more variable (p ≤ 0,05). Go120,8º and 125,1º. Significant of the angles of the canines according to the basal arch of the lower jaw of 102,8º and 105,4º (p≤0.01) and the angle of inclination of the first permanent molars of 89,6º and 91,4º, respectively (p≤0.01). CONCLUSION: Conclusions: The obtained data indicate that there is no clear correlation between changes in the studied parameters and the localization of anomalies (left-sided, right-sided). Indicators of the angle of the lower jaw are significantly altered from the opposite direction of its displacement. The change in the angles of inclination of the canine and the first permanent molars, as occlusive compensation, is determined reliably. The more the angle of the mandible changes, the more the lower jaw moves in the transversal direction. Perhaps this is due to the asymmetric tone of masticatory muscles.

Analysis of the results of the questionnaire of orthodontists and children dentists of poltava-city on the optimization of orthodontic aids for children.

OBJECTIVE: Introduction: In the course of the study, we identified high prevalence rates of orthodontic pathology and identified organizational aspects regarding the provision of orthodontic care for children, and identified the need for their optimization. The aim: The purpose of the study was to analyze the results of the questionnaire of orthodontists and children's dentists, who provide dental care to the children of the Poltava region, about the importance of optimization of orthodontic care for children and improving the knowledge of doctors about the risk factors for the onset of orthodontic pathology. PATIENTS AND METHODS: Materials and methods: Methods: Sociological (questionnaire), medical-statistical, bibliosemantic. We analyze 39 questionnaires, which filled out by orthodontists and children's dentists who provide dental care to children of the Poltava region. RESULTS: Results: A questionnaire was conducted for 39 children's dentists of different specialties, and the subject for study of which was the knowledge of doctors about the risk factors for the occurrence of orthodontic pathology; the opinion of specialists on optimization of the system of prevention, dyspanserization, screening and sanitary-education work. The results of the questionnaire were processed with using of statistical methods and analyzed. CONCLUSION: Conclusions: 1. Most doctors consider the most important influencing risk factors that relate to behavioral, informational and medical-demographic, that is, those that are managed. 2. Most doctors determine the existing system of orthodontic care as ineffective, recognize the effectiveness of a joint prevention, dispensary and screening program; consider it advisable to create a single electronic medical card for the child from birth; the level of awareness of the population is low; it is expedient to involve in the preventive and sanitary-educational work of dental hygienists to reduce the burden on doctors. 3. In the training of students and interns in the specialty "Dentistry", more attention should be paid to the study of the risk factors of the occurrence of orthodontic pathology and the importance of primary prevention and dyspansery control to reduce its level.